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rs2236225(C;T)

From SNPedia

Possible increased risk of birth defects
Is agenotype
ofrs2236225
GeneMTHFD1
Chromosome14
Position64,442,127
mentionedby
Magnitude1.25
ReputeBad
Geno Mag Summary
(C;C) 0 common/normal
(C;T) 1.25 Possible increased risk of birth defects
(T;T) 1.5 Slightly (~1.5x) higher risk for Caucasian mothers to give birth to NTD children

Some studies, predominanty amongst Caucasians, have shown that presence of this mutation is associated with a slightly higher risk to give birth to children with neural tube defects; other studies have demonstrated association with heart defects in homozygous offspring - See discussion at rs2236225.