Have questions? Visit https://www.reddit.com/r/SNPedia

rs2238135

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) normal risk
(C;G)  ?
(G;G) 2.47x higher risk for prostate cancer
ReferenceGRCh38 38.1/141
Chromosome12
Position47884407
GeneVDR
is asnp
is mentioned by
dbSNPrs2238135
ebirs2238135
HLIrs2238135
Exacrs2238135
Varsomers2238135
Maprs2238135
PheGenIrs2238135
hapmaprs2238135
1000 genomesrs2238135
hgdprs2238135
ensemblrs2238135
gopubmedrs2238135
geneviewrs2238135
scholarrs2238135
googlers2238135
pharmgkbrs2238135
gwascentralrs2238135
openSNPrs2238135
23andMers2238135
23andMe allrs2238135
SNP Nexus

SNPshotrs2238135
SNPdbers2238135
MSV3drs2238135
GWAS Ctlgrs2238135
GMAF0.2456
Max Magnitude
rs2238135 is a SNP in the vitamin D VDR receptor gene.

rs2238135(G;G) homozygotes were associated with an ~2.5x higher risk of prostate cancer compared to homozygote carriers of the more common (C) allele in the 630 Caucasian patients studied.[PMID 17932346]


[PMID 17130574] Protection from type 1 diabetes by vitamin D receptor haplotypes.


[PMID 19255064OA-icon.png] Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.


[PMID 19454612OA-icon.png] Vitamin D pathway gene variants and prostate cancer risk.


[PMID 19753122OA-icon.png] Analysis of SNPs and haplotypes in vitamin D pathway genes and renal cancer risk.


[PMID 23189278] VDR gene single nucleotide polymorphisms and their association with risk of oral cavity carcinoma