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rs2240335

From SNPedia

Orientationminus
Stabilizedminus
Make rs2240335(G;G)
Make rs2240335(G;T)
Make rs2240335(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position17348042
GenePADI4
is asnp
is mentioned by
dbSNPrs2240335
ebirs2240335
HLIrs2240335
Exacrs2240335
Varsomers2240335
Maprs2240335
PheGenIrs2240335
hapmaprs2240335
1000 genomesrs2240335
hgdprs2240335
ensemblrs2240335
gopubmedrs2240335
geneviewrs2240335
scholarrs2240335
googlers2240335
pharmgkbrs2240335
gwascentralrs2240335
openSNPrs2240335
23andMers2240335
23andMe allrs2240335
SNP Nexus

SNPshotrs2240335
SNPdbers2240335
MSV3drs2240335
GWAS Ctlgrs2240335
GMAF0.4224
Max Magnitude
? (G;G) (G;T) (T;T) 28
Rs2240335
PubMed [PMID 12833157]
Affy Probeset SNP_A-8556874
Affy Orientation same
On GW 5.0 0
Alleles A/B G/T
Ancestral G
Population Japan
Allele G
Case Freq.
Control Freq.
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All 1.75
Disease Rheumatoid Arthritis (RA)


rs2240335 is in linkage disequilibrium with a polymorphism that increases susceptibility to Rheumatoid Arthritis 1.75 times for carriers of the G allele [PMID 12833157]

Neighborrs2240338
Distance352
GWAS snp
PMID [PMID 21225715]
Trait
Title Genome-wide association study of rheumatoid arthritis in Korea: Population-specific loci as well as overlap with European susceptibility loci
Risk Allele
P-val 2E-8
Odds Ratio 1.5000 [NR]
GWAS snp
PMID [PMID 21505073]
Trait
Title The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Risk Allele
P-val 2E-8
Odds Ratio None None
GWAS snp
PMID [PMID 21452313]
Trait
Title Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.
Risk Allele
P-val 2E-8
Odds Ratio 1.5000 [NR]