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rs2271293

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common on affy axiom data
Make rs2271293(A;A)
Make rs2271293(A;G)
ReferenceGRCh38 38.1/141
Chromosome16
Position67868167
GeneNUTF2
is asnp
is mentioned by
dbSNPrs2271293
ebirs2271293
HLIrs2271293
Exacrs2271293
Varsomers2271293
Maprs2271293
PheGenIrs2271293
hapmaprs2271293
1000 genomesrs2271293
hgdprs2271293
ensemblrs2271293
gopubmedrs2271293
geneviewrs2271293
scholarrs2271293
googlers2271293
pharmgkbrs2271293
gwascentralrs2271293
openSNPrs2271293
23andMers2271293
23andMe allrs2271293
SNP Nexus

SNPshotrs2271293
SNPdbers2271293
MSV3drs2271293
GWAS Ctlgrs2271293
GMAF0.09091
Max Magnitude0
? (A;A) (A;G) (G;G) 28
per the 23andMe blog, the minor allele of this SNP (A) was associated with decreased LDL cholesterol, increased HDL, and decreased triglycerides
SNP Rarer allele LDL HDL TG
rs6544713 T +
rs2650000 A +
rs471364 C -
rs1800961 T -
rs7679 C - +
rs2967605 T -
rs2409722 T -
rs10903129 A - - -
rs6756629 A - + -
rs12670798 C + + +
rs7395662 A - + +
rs174570 T - - +
rs2271293 A - + -
rs2624265 C +
rs2167079 T +
rs9891572 T +
rs4844614 T +
rs5031002 G +
GWAS snp
PMID [PMID 19060911OA-icon.png]
Trait HDL cholesterol
Title Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
Risk Allele G
P-val 8E-16
Odds Ratio 0.13 [NR] SD decrease
GWAS snp
PMID [PMID 19060906OA-icon.png]
Trait HDL cholesterol
Title Common variants at 30 loci contribute to polygenic dyslipidemia
Risk Allele A
P-val 9E-13
Odds Ratio 0.07 [0.01-0.13] SD increase



OMIM607687
Desc
Variant
Relatedalso
[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.


[PMID 20160193OA-icon.png] Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.


[PMID 20385826OA-icon.png] Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).


[PMID 20502693OA-icon.png] Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.


GET Evidence
rs2271293
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.101562
summary