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rs2272383

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) normal risk
(A;G) higher body mass index
(G;G) higher body mass index
ReferenceGRCh38 38.1/141
Chromosome11
Position8101952
GeneRIC3, TUB
is asnp
is mentioned by
dbSNPrs2272383
ebirs2272383
HLIrs2272383
Exacrs2272383
Varsomers2272383
Maprs2272383
PheGenIrs2272383
hapmaprs2272383
1000 genomesrs2272383
hgdprs2272383
ensemblrs2272383
gopubmedrs2272383
geneviewrs2272383
scholarrs2272383
googlers2272383
pharmgkbrs2272383
gwascentralrs2272383
openSNPrs2272383
23andMers2272383
23andMe allrs2272383
SNP Nexus

SNPshotrs2272383
SNPdbers2272383
MSV3drs2272383
GWAS Ctlgrs2272383
GMAF0.4394
Max Magnitude
? (A;A) (A;G) (G;G) 28
rs2272383, a SNP in the TUB gene, was found in a study of 492 unrelated type-2 diabetes patients to have a significant effect on body mass index and thus obesity (1.3 kg/m(2), p= 0.01). When two populations were combined, totaling ~1200 patients, the risk allele rs2272383(G) averaged an increase of 0.21 (–0.28 to 0.70).[PMID 16443771]


[PMID 17955208] TUB is a candidate gene for late-onset obesity in women.


[PMID 18183286OA-icon.png] Polymorphisms of the TUB gene are associated with body composition and eating behavior in middle-aged women.