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rs227584

From SNPedia

Orientationminus
Stabilizedminus
Make rs227584(G;G)
Make rs227584(G;T)
Make rs227584(T;T)
ReferenceGRCh38 38.1/141
Chromosome17
Position44148179
GeneC17orf53
is asnp
is mentioned by
dbSNPrs227584
ebirs227584
HLIrs227584
Exacrs227584
Varsomers227584
Maprs227584
PheGenIrs227584
hapmaprs227584
1000 genomesrs227584
hgdprs227584
ensemblrs227584
gopubmedrs227584
geneviewrs227584
scholarrs227584
googlers227584
pharmgkbrs227584
gwascentralrs227584
openSNPrs227584
23andMers227584
23andMe allrs227584
SNP Nexus

SNPshotrs227584
SNPdbers227584
MSV3drs227584
GWAS Ctlgrs227584
GMAF0.4256
Max Magnitude
? (G;G) (G;T) (T;T) 28
GWAS snp
PMID [PMID 19079262]
Trait Bone mineral density (hip)
Title New sequence variants associated with bone mineral density
Risk Allele T
P-val 9E-7
Odds Ratio 0.07 [0.04-0.10] SD decrease



[PMID 19801982OA-icon.png] Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.

GWAS snp
PMID [PMID 22504420OA-icon.png]
Trait
Title Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Risk Allele A
P-val 3E-24
Odds Ratio 0.0600 None


GET Evidence
C17ORF53-T126P
aa_change Thr126Pro
aa_change_short T126P
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.475088
summary