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rs2281135

From SNPedia

Orientationminus
Stabilizedminus
Make rs2281135(C;C)
Make rs2281135(C;T)
Make rs2281135(T;T)
ReferenceGRCh38 38.1/141
Chromosome22
Position43936690
GenePNPLA3
is asnp
is mentioned by
dbSNPrs2281135
ebirs2281135
HLIrs2281135
Exacrs2281135
Varsomers2281135
Maprs2281135
PheGenIrs2281135
hapmaprs2281135
1000 genomesrs2281135
hgdprs2281135
ensemblrs2281135
gopubmedrs2281135
geneviewrs2281135
scholarrs2281135
googlers2281135
pharmgkbrs2281135
gwascentralrs2281135
openSNPrs2281135
23andMers2281135
23andMe allrs2281135
SNP Nexus

SNPshotrs2281135
SNPdbers2281135
MSV3drs2281135
GWAS Ctlgrs2281135
GMAF0.2723
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 18940312OA-icon.png]
Trait Plasma levels of liver enzymes
Title Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes
Risk Allele T
P-val 8E-16
Odds Ratio 0.06 [0.046-0.074] U/L increase
OMIM612364
DescALANINE AMINOTRANSFERASE, PLASMA LEVEL OF, QUANTITATIVE TRAIT LOCUS
Variant
Relatedalso
[PMID 19474294OA-icon.png] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.


GET Evidence
rs2281135
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.21875
summary



[PMID 22863562OA-icon.png] PNPLA3 polymorphisms and liver aminotransferase levels in a Mexican American population.