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rs2283265

From SNPedia

Orientationminus
Stabilizedminus
Make rs2283265(G;G)
Make rs2283265(G;T)
Make rs2283265(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position113414814
GeneDRD2
is asnp
is mentioned by
dbSNPrs2283265
ebirs2283265
HLIrs2283265
Exacrs2283265
Varsomers2283265
Maprs2283265
PheGenIrs2283265
hapmaprs2283265
1000 genomesrs2283265
hgdprs2283265
ensemblrs2283265
gopubmedrs2283265
geneviewrs2283265
scholarrs2283265
googlers2283265
pharmgkbrs2283265
gwascentralrs2283265
openSNPrs2283265
23andMers2283265
23andMe allrs2283265
SNP Nexus

SNPshotrs2283265
SNPdbers2283265
MSV3drs2283265
GWAS Ctlgrs2283265
GMAF0.2117
Max Magnitude
? (G;G) (G;T) (T;T) 28
[PMID 19772578OA-icon.png] Two-stage case-control association study of dopamine-related genes and migraine



[PMID 18077373OA-icon.png] Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.


[PMID 18332877OA-icon.png] Family-based association testing strongly implicates DRD2 as a risk gene for schizophrenia in Han Chinese from Taiwan.


[PMID 19321766OA-icon.png] Dopamine DRD2 polymorphism alters reversal learning and associated neural activity.


[PMID 19393722OA-icon.png] Genetic contributions to avoidance-based decisions: striatal D2 receptor polymorphisms.


[PMID 20179754OA-icon.png] Genetically determined measures of striatal D2 signaling predict prefrontal activity during working memory performance.


[PMID 20617039OA-icon.png] Alcoholism and alternative splicing of candidate genes.


[PMID 21150907OA-icon.png] Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse.


GET Evidence
rs2283265
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.1875
summary



[PMID 23340505OA-icon.png] Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction


[PMID 24322206] Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain


[PMID 22579533] Binge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypes.


[PMID 23635803] ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse.


[PMID 24780147] Association of dopamine gene variants, emotion dysregulation and ADHD in autism spectrum disorder


[PMID 24495967OA-icon.png] Common polymorphisms in dopamine-related genes combine to produce a 'schizophrenia-like' prefrontal hypoactivity


[PMID 25875614] Overlapping Dopaminergic Pathway Genetic Susceptibility to Heroin and Cocaine Addictions in African Americans