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rs2286812

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common
(C;T) 1.5 ~2x higher risk for Fuchs' dystrophy, a corneal disorder
(T;T) 2 ~4x higher risk for Fuchs' dystrophy, a corneal disorder
ReferenceGRCh38 38.1/141
Chromosome18
Position56050233
GeneRPL12P10
is asnp
is mentioned by
dbSNPrs2286812
ebirs2286812
HLIrs2286812
Exacrs2286812
Varsomers2286812
Maprs2286812
PheGenIrs2286812
hapmaprs2286812
1000 genomesrs2286812
hgdprs2286812
ensemblrs2286812
gopubmedrs2286812
geneviewrs2286812
scholarrs2286812
googlers2286812
pharmgkbrs2286812
gwascentralrs2286812
openSNPrs2286812
23andMers2286812
23andMe allrs2286812
SNP Nexus

SNPshotrs2286812
SNPdbers2286812
MSV3drs2286812
GWAS Ctlgrs2286812
GMAF0.1088
Max Magnitude2
rs2286812 is a SNP in the transcription factor 4 TCF4 gene. It is one of several TCF4 SNPs reported to be independently associated with Fuchs' dystrophy.
? (C;C) (C;T) (T;T) 28
[PMID 22234156OA-icon.png] Association of TCF4 and CLU polymorphisms with Fuchs' endothelial dystrophy and implication of CLU and TGFBI proteins in the disease process