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rs2287499

From SNPedia

Orientationminus
Stabilizedminus
Make rs2287499(C;C)
Make rs2287499(C;G)
Make rs2287499(G;G)
ReferenceGRCh38 38.1/141
Chromosome17
Position7688850
GeneTP53
is asnp
is mentioned by
dbSNPrs2287499
ebirs2287499
HLIrs2287499
Exacrs2287499
Varsomers2287499
Maprs2287499
PheGenIrs2287499
hapmaprs2287499
1000 genomesrs2287499
hgdprs2287499
ensemblrs2287499
gopubmedrs2287499
geneviewrs2287499
scholarrs2287499
googlers2287499
pharmgkbrs2287499
gwascentralrs2287499
openSNPrs2287499
23andMers2287499
23andMe allrs2287499
SNP Nexus

SNPshotrs2287499
SNPdbers2287499
MSV3drs2287499
GWAS Ctlgrs2287499
GMAF0.3379
Max Magnitude
? (C;C) (C;G) (G;G) 28

[PMID 17683073] ER negative breast cancer association rs2287499, OR (95% CI) = 1.08 (0.95-1.23) for CG vs. CC and 1.60 (1.04-2.47) for GG vs. CC, p-trend = 0.01) (OR (95% CI) per variant allele: 1.42 (1.18-1.71) p-trend = 0.00009).


[PMID 17151932] Genetic variation in p53 and ATM haplotypes and risk of glioma and meningioma.


[PMID 17428325OA-icon.png] Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.


[PMID 18978339OA-icon.png] Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.


[PMID 19276375OA-icon.png] Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer.


[PMID 20386703OA-icon.png] Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer.


[PMID 25134915] Single-strand conformational polymorphism analysis of a common single nucleotide variation in WRAP53 gene, rs2287499, and evaluating its association in relation to breast cancer risk and prognosis among Iranian-Azeri population