|?|| (C;C) (C;T) (T;T) ||28|
has been associated with hypertension
. In genotypic combination with rs4149601
it was associated with systolic blood pressure (SBP) (p=0.01), DBP (p=0.04), and progression of both SBP (p=0.03) and DBP (p=0.05) over time.[PMID 16788695
[PMID 20003179] Genetic variation of NEDD4L is associated with essential hypertension in female Kazakh general population: a case-control study
[PMID 17044734] European population substructure: clustering of northern and southern populations.
[PMID 17487281] Polymorphism in NEDD4L is associated with increased salt sensitivity, reduced levels of P-renin and increased levels of Nt-proANP.
[PMID 23549273] A Functional Variant of NEDD4L Is Associated with Obesity and Related Phenotypes in a Han Population of Southern China.
[PMID 24446284] Gender flip-flop association between genetic variations of NEDD4L and metabolic syndrome in the Kazakh general population