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rs2288774

From SNPedia

Orientationplus
Stabilizedplus
Make rs2288774(C;C)
Make rs2288774(C;T)
Make rs2288774(T;T)
ReferenceGRCh38 38.1/141
Chromosome18
Position58316098
GeneNEDD4L
is asnp
is mentioned by
dbSNPrs2288774
ebirs2288774
HLIrs2288774
Exacrs2288774
Varsomers2288774
Maprs2288774
PheGenIrs2288774
hapmaprs2288774
1000 genomesrs2288774
hgdprs2288774
ensemblrs2288774
gopubmedrs2288774
geneviewrs2288774
scholarrs2288774
googlers2288774
pharmgkbrs2288774
gwascentralrs2288774
openSNPrs2288774
23andMers2288774
23andMe allrs2288774
SNP Nexus

SNPshotrs2288774
SNPdbers2288774
MSV3drs2288774
GWAS Ctlgrs2288774
GMAF0.4784
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs2288774 has been associated with hypertension. In genotypic combination with rs4149601 it was associated with systolic blood pressure (SBP) (p=0.01), DBP (p=0.04), and progression of both SBP (p=0.03) and DBP (p=0.05) over time.[PMID 16788695]


[PMID 20003179OA-icon.png] Genetic variation of NEDD4L is associated with essential hypertension in female Kazakh general population: a case-control study

[PMID 17044734OA-icon.png] European population substructure: clustering of northern and southern populations.

[PMID 17487281OA-icon.png] Polymorphism in NEDD4L is associated with increased salt sensitivity, reduced levels of P-renin and increased levels of Nt-proANP.


[PMID 23549273OA-icon.png] A Functional Variant of NEDD4L Is Associated with Obesity and Related Phenotypes in a Han Population of Southern China.


[PMID 24446284] Gender flip-flop association between genetic variations of NEDD4L and metabolic syndrome in the Kazakh general population