[PMID 22006848] Genetic and epigenetic associations of circadian gene TIMELESS and breast cancer risk
GWAS snp
|
PMID
|
[PMID 24144296]
|
Trait
|
Axial length
|
Title
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Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
|
Risk Allele
|
T
|
P-val
|
4E-7
|
Odds Ratio
|
.05 [0.032-0.072] unit increase
|
[PMID 18228528] Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm.
[PMID 19166596] Circadian polymorphisms associated with affective disorders.
[PMID 19470168] NPAS2 and PER2 are linked to risk factors of the metabolic syndrome.
[PMID 20174623] Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance.
[PMID 20180986] CLOCK is suggested to associate with comorbid alcohol use and depressive disorders.
[PMID 20668683] Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk.