|?|| (A;A) (A;G) (G;G) ||28|
[PMID 22006848] Genetic and epigenetic associations of circadian gene TIMELESS and breast cancer risk
|| [PMID 24144296]
|| Axial length
|| Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
| Risk Allele
| Odds Ratio
|| .05 [0.032-0.072] unit increase
[PMID 18228528] Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm.
[PMID 19166596] Circadian polymorphisms associated with affective disorders.
[PMID 19470168] NPAS2 and PER2 are linked to risk factors of the metabolic syndrome.
[PMID 20174623] Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance.
[PMID 20180986] CLOCK is suggested to associate with comorbid alcohol use and depressive disorders.
[PMID 20668683] Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk.