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rs229541

From SNPedia

Orientationminus
Stabilizedminus
Make rs229541(C;C)
Make rs229541(C;T)
Make rs229541(T;T)
ReferenceGRCh38 38.1/141
Chromosome22
Position37195278
is asnp
is mentioned by
dbSNPrs229541
ebirs229541
HLIrs229541
Exacrs229541
Varsomers229541
Maprs229541
PheGenIrs229541
hapmaprs229541
1000 genomesrs229541
hgdprs229541
ensemblrs229541
gopubmedrs229541
geneviewrs229541
scholarrs229541
googlers229541
pharmgkbrs229541
gwascentralrs229541
openSNPrs229541
23andMers229541
23andMe allrs229541
SNP Nexus

SNPshotrs229541
SNPdbers229541
MSV3drs229541
GWAS Ctlgrs229541
GMAF0.4371
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 18978792OA-icon.png]
Trait Type 1 diabetes
Title Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
Risk Allele T
P-val 2E-8
Odds Ratio 1.04 [0.97-1.12]
GWAS snp
PMID [PMID 19430480OA-icon.png]
Trait Type 1 diabetes
Title Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
Risk Allele
P-val 2E-7
Odds Ratio NR NR
OMIM222100
DescDIABETES MELLITUS, INSULIN-DEPENDENT; IDDM
Variant
Relatedalso
[PMID 19073967OA-icon.png] Shared and distinct genetic variants in type 1 diabetes and celiac disease.


[PMID 19168599OA-icon.png] Type 1 diabetes in the BB rat: a polygenic disease.


[PMID 19474294OA-icon.png] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.


[PMID 19966805OA-icon.png] The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.


GET Evidence
rs229541
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.523438
summary



[PMID 24367383OA-icon.png] Evidence of Stage- and Age-Related Heterogeneity of Non-HLA SNPs and Risk of Islet Autoimmunity and Type 1 Diabetes: The Diabetes Autoimmunity Study in the Young