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rs2298668

From SNPedia

Merged intors2229437
Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0 common in complete genomics
Make rs2298668(A;C)
Make rs2298668(C;C)
ReferenceGRCh38 38.1/141
Chromosome11
Position82853252
GenePRCP
is asnp
is mentioned by
dbSNPrs2298668
ebirs2298668
HLIrs2298668
Exacrs2298668
Varsomers2298668
Maprs2298668
PheGenIrs2298668
hapmaprs2298668
1000 genomesrs2298668
hgdprs2298668
ensemblrs2298668
gopubmedrs2298668
geneviewrs2298668
scholarrs2298668
googlers2298668
pharmgkbrs2298668
gwascentralrs2298668
openSNPrs2298668
23andMers2298668
23andMe allrs2298668
SNP Nexus

SNPshotrs2298668
SNPdbers2298668
MSV3drs2298668
GWAS Ctlgrs2298668
StatusMerged into rs2229437
GMAF0.1383
Max Magnitude0
? (A;A) (A;C) (C;C) 28

Women with the snp has been linked to significant risk of a premature birth [PMID 16681991]

These press releases explain it more simply

The risky variation is 3x more common in women of african descent.

  • rs2298668 Prolylcarboxypepdiase E112D (rs2298668)D allele alone and jointly with chronic hypertension were associated with a significantly increased risk of preeclampsia

[PMID 16642433OA-icon.png] Polymorphism in maternal LRP8 gene is associated with fetal growth.


GET Evidence
PRCP-E112D
aa_change Glu112Asp
aa_change_short E112D
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.160067
summary