Have questions? Visit https://www.reddit.com/r/SNPedia

rs2302254

From SNPedia

Orientationplus
Stabilizedplus
Make rs2302254(C;C)
Make rs2302254(C;T)
Make rs2302254(T;T)
ReferenceGRCh38 38.1/141
Chromosome17
Position51153539
GeneNME1, NME1-NME2
is asnp
is mentioned by
dbSNPrs2302254
ebirs2302254
HLIrs2302254
Exacrs2302254
Varsomers2302254
Maprs2302254
PheGenIrs2302254
hapmaprs2302254
1000 genomesrs2302254
hgdprs2302254
ensemblrs2302254
gopubmedrs2302254
geneviewrs2302254
scholarrs2302254
googlers2302254
pharmgkbrs2302254
gwascentralrs2302254
openSNPrs2302254
23andMers2302254
23andMe allrs2302254
SNP Nexus

SNPshotrs2302254
SNPdbers2302254
MSV3drs2302254
GWAS Ctlgrs2302254
GMAF0.2479
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 18676749OA-icon.png] breast cancer 1,134 breast cancer patients recruited as part of the Shanghai Breast Cancer Study who were followed for a median of 7.1 years. rs2302254 was also associated with breast cancer (HR, 1.3; 95% CI, 1.0-1.6). strong linkage disequilibrium for rs16949646 rs2302254 and rs3760468

[PMID 21824052] Acute myeloid leukemia patients carrying rs2302254(T) alleles are at much higher risk of developing neurotoxic side effects if treated with Ara-C (cytarabine), compared to those not carrying a (T) allele.

Neighborrs3760468
Distance409


[PMID 20599259] Significant association of genetic polymorphism of human nonmetastatic clone 23 type 1 gene with an increased risk of endometrial cancer


[PMID 22035418] The T_T genotype within the NME1 promoter SNP -835 C/T is associated with an increased risk of Ara-C induced neurotoxicity in AML patients


[PMID 20601538] Polymorphisms of human nonmetastatic clone 23 type 1 gene and neoplastic lesions of uterine cervix.


[PMID 22683585] nm23 gene polymorphisms are associated with survival of patients with epithelial ovarian cancer but not with susceptibility to disease.


[PMID 22903495] Associations of non-metastatic cells 1 gene polymorphisms with lymph node metastasis risk of gastric cancer in Northern Chinese population.