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rs2305160

From SNPedia

Orientationminus
Stabilizedminus
Make rs2305160(C;C)
Make rs2305160(C;T)
Make rs2305160(T;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position100974842
GeneAC016738.3, NPAS2
is asnp
is mentioned by
dbSNPrs2305160
ebirs2305160
HLIrs2305160
Exacrs2305160
Varsomers2305160
Maprs2305160
PheGenIrs2305160
hapmaprs2305160
1000 genomesrs2305160
hgdprs2305160
ensemblrs2305160
gopubmedrs2305160
geneviewrs2305160
scholarrs2305160
googlers2305160
pharmgkbrs2305160
gwascentralrs2305160
openSNPrs2305160
23andMers2305160
23andMe allrs2305160
SNP Nexus

SNPshotrs2305160
SNPdbers2305160
MSV3drs2305160
GWAS Ctlgrs2305160
GMAF0.2314
Max Magnitude
? (C;C) (C;T) (T;T) 28

[PMID 21140207] A variant affecting miRNAs binding in the circadian gene Neuronal PAS domain protein 2 (NPAS2) is not associated with breast cancer risk

[PMID 17096334OA-icon.png] Ala394Thr polymorphism in the clock gene NPAS2: a circadian modifier for the risk of non-Hodgkin's lymphoma.

[PMID 17984998] Variants in circadian genes and prostate cancer risk: a population-based study in China.

[PMID 18990770] Correlation between circadian gene variants and serum levels of sex steroids and insulin-like growth factor-I.

[PMID 19470168OA-icon.png] NPAS2 and PER2 are linked to risk factors of the metabolic syndrome.

[PMID 20180986OA-icon.png] CLOCK is suggested to associate with comorbid alcohol use and depressive disorders.

[PMID 20368993OA-icon.png] ARNTL (BMAL1) and NPAS2 gene variants contribute to fertility and seasonality.


GET Evidence
NPAS2-T394A
aa_change Thr394Ala
aa_change_short T394A
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.746607
summary



[PMID 24754267OA-icon.png] Functional polymorphisms in NPAS2 gene are associated with overall survival in TACE-treated hepatocellular carcinoma patients


[PMID 25227809] Lack of Association of the NPAS2 Gene Ala394Thr Polymorphism (rs2305160:G>A) with Risk of Chronic Lymphocytic Leukemia


[PMID 24824748] Association between restless legs syndrome and CLOCK and NPAS2 gene polymorphisms in schizophrenia