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rs2305795

From SNPedia

narcolepsy
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 1.64x higher risk of narcolepsy compared to (G;G) genotype
(A;G) 2 1.28x higher risk of narcolepsy compared to (G;G) genotype
(G;G) 0 normal risk of narcolepsy
ReferenceGRCh38 38.1/141
Chromosome19
Position10115376
GeneEIF3G, PPAN-P2RY11, P2RY11
is asnp
is mentioned by
dbSNPrs2305795
ebirs2305795
HLIrs2305795
Exacrs2305795
Varsomers2305795
Maprs2305795
PheGenIrs2305795
hapmaprs2305795
1000 genomesrs2305795
hgdprs2305795
ensemblrs2305795
gopubmedrs2305795
geneviewrs2305795
scholarrs2305795
googlers2305795
pharmgkbrs2305795
gwascentralrs2305795
openSNPrs2305795
23andMers2305795
23andMe allrs2305795
SNP Nexus

SNPshotrs2305795
SNPdbers2305795
MSV3drs2305795
GWAS Ctlgrs2305795
GMAF0.3623
Max Magnitude2
? (A;A) (A;G) (G;G) 28
Common variants in P2RY11 are associated with narcolepsy. [PMID 21170044OA-icon.png] Found that rs2305795 G allele appears to lower the risk of narcolepsy.

This SNP is also in the intronal area of the EIF3G gene.


[PMID 22177342OA-icon.png] TCRA, P2RY11, and CPT1B/CHKB associations in Chinese narcolepsy.


[PMID 25669430] EIF3G is associated with narcolepsy across ethnicities


ClinVar
Risk rs2305795(A;A)
Alt rs2305795(A;A)
Reference rs2305795(G;G)
Significance Other
Disease Cataplexy and narcolepsy
Variation info
Gene P2RY11 EIF3G PPAN-P2RY11
CLNDBN Cataplexy and narcolepsy
Reversed 0
HGVS NC_000019.9:g.10226052G>A
CLNSRC
CLNACC RCV000161132.1,