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rs2306536

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 average
(C;T)  ?
(T;T) 0.5x lower risk of colorectal cancer
ReferenceGRCh38 38.1/141
Chromosome12
Position132847076
GeneCHFR
is asnp
is mentioned by
dbSNPrs2306536
ebirs2306536
HLIrs2306536
Exacrs2306536
Varsomers2306536
Maprs2306536
PheGenIrs2306536
hapmaprs2306536
1000 genomesrs2306536
hgdprs2306536
ensemblrs2306536
gopubmedrs2306536
geneviewrs2306536
scholarrs2306536
googlers2306536
pharmgkbrs2306536
gwascentralrs2306536
openSNPrs2306536
23andMers2306536
23andMe allrs2306536
SNP Nexus

SNPshotrs2306536
SNPdbers2306536
MSV3drs2306536
GWAS Ctlgrs2306536
GMAF0.1662
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs2306536, a SNP in the CHFR gene, was found to be significantly associated with a lower risk of colorectal cancer (odd ratio 0.53, CI: 0.30-0.94), and to be significantly correlated with the absence of distant metastases, in a case/control study of ~500 Korean patients. [PMID 18079053]


GET Evidence
CHFR-V539M
aa_change Val539Met
aa_change_short V539M
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.18254
summary