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rs2313982

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs2313982(C;T)
Make rs2313982(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position137866906
is asnp
is mentioned by
dbSNPrs2313982
ebirs2313982
HLIrs2313982
Exacrs2313982
Varsomers2313982
Maprs2313982
PheGenIrs2313982
hapmaprs2313982
1000 genomesrs2313982
hgdprs2313982
ensemblrs2313982
gopubmedrs2313982
geneviewrs2313982
scholarrs2313982
googlers2313982
pharmgkbrs2313982
gwascentralrs2313982
openSNPrs2313982
23andMers2313982
23andMe allrs2313982
SNP Nexus

SNPshotrs2313982
SNPdbers2313982
MSV3drs2313982
GWAS Ctlgrs2313982
GMAF0.08127
Max Magnitude0

Although an initial report in 2005 found an association between the minor allele of rs2313982 and Parkinson's disease, subsequent reports have not found any statistically significant association, most notably a meta-analysis totaling over 3,000 patients published in 2010.

? (C;C) (C;T) (T;T) 28
Rs2313982
PubMed [PMID 16252231OA-icon.png]
Affy Probeset SNP_A-4264503
Affy Orientation same
On GW 5.0
Alleles A/B C/T
Ancestral
Population
Allele T
Case Freq. 0.12
Control Freq. 0.06
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All 2.01
Disease Parkinson's disease (PKD)


[PMID 16685661OA-icon.png] Genomewide association, Parkinson disease, and PARK10.


[PMID 16685662OA-icon.png] No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening.


[PMID 16685663OA-icon.png] A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan.


[PMID 17332845OA-icon.png] Meta-analysis in genome-wide association datasets: strategies and application in Parkinson disease.


[PMID 19475631] Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study.