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rs236114

From SNPedia

Orientationminus
Stabilizedminus
Make rs236114(A;A)
Make rs236114(A;G)
Make rs236114(G;G)
ReferenceGRCh38 38.1/141
Chromosome20
Position5954739
GeneMCM8
is asnp
is mentioned by
dbSNPrs236114
ebirs236114
HLIrs236114
Exacrs236114
Varsomers236114
Maprs236114
PheGenIrs236114
hapmaprs236114
1000 genomesrs236114
hgdprs236114
ensemblrs236114
gopubmedrs236114
geneviewrs236114
scholarrs236114
googlers236114
pharmgkbrs236114
gwascentralrs236114
openSNPrs236114
23andMers236114
23andMe allrs236114
SNP Nexus

SNPshotrs236114
SNPdbers236114
MSV3drs236114
GWAS Ctlgrs236114
GMAF0.1079
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19448619OA-icon.png]
Trait Menopause
Title Loci at chromosomes 13, 19 and 20 influence age at natural menopause.
Risk Allele A
P-val 1E-10
Odds Ratio 0.50 [0.34-0.65] years older
OMIM612885
Desc
Variant
Relatedalso
[PMID 17186469OA-icon.png] Mutations in the gene encoding the Wnt-signaling component R-spondin 4 (RSPO4) cause autosomal recessive anonychia.


[PMID 19664201OA-icon.png] Genetic and genomic insights into age at natural menopause.


GET Evidence
rs236114
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.831753
summary



[PMID 23360674] Genetic variation may modify ovarian reserve in female childhood cancer survivors.