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rs2363956

From SNPedia

Orientationplus
Stabilizedplus
Make rs2363956(G;G)
Make rs2363956(G;T)
Make rs2363956(T;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position17283315
GeneANKLE1
is asnp
is mentioned by
dbSNPrs2363956
ebirs2363956
HLIrs2363956
Exacrs2363956
Varsomers2363956
Maprs2363956
PheGenIrs2363956
hapmaprs2363956
1000 genomesrs2363956
hgdprs2363956
ensemblrs2363956
gopubmedrs2363956
geneviewrs2363956
scholarrs2363956
googlers2363956
pharmgkbrs2363956
gwascentralrs2363956
openSNPrs2363956
23andMers2363956
23andMe allrs2363956
SNP Nexus

SNPshotrs2363956
SNPdbers2363956
MSV3drs2363956
GWAS Ctlgrs2363956
GMAF0.4504
Max Magnitude
? (G;G) (G;T) (T;T) 28
breast cancer http://www.nature.com/ng/journal/v42/n10/full/ng.669.html

This SNP is associated with risk of breast cancer. [PMID 20852631OA-icon.png]

GWAS snp
PMID [PMID 20852633OA-icon.png]
Trait
Title Common variants at 19p13 are associated with susceptibility to ovarian cancer
Risk Allele T
P-val 1E-7
Odds Ratio 1.10 [1.06-1.15]


[PMID 22235027OA-icon.png] Evaluation of microRNA expression profiles and their associations with risk alleles in lymphoblastoid cell lines of familial ovarian cancer.


GET Evidence
ANKLE1-L184W
aa_change Leu184Trp
aa_change_short L184W
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.513481
summary



[PMID 23133607OA-icon.png] Associations between gene expression variations and ovarian cancer risk alleles identified from genome wide association studies.

GWAS snp
PMID [PMID 24325915OA-icon.png]
Trait Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative)
Title Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.
Risk Allele C
P-val 2E-8
Odds Ratio 1.22 [1.14-1.3]


[PMID 25173882OA-icon.png] Replication Study for the Association of Seven Genome- Gwas-Identified Loci With Susceptibility to Ovarian Cancer in the Polish Population