|?|| (C;C) (C;T) (T;T) ||28|
|| [PMID 20453838]
|| Breast cancer
|| Genome-wide association study identifies five new breast cancer susceptibility loci
| Risk Allele
| Odds Ratio
|| 1.06 [1.02-1.10]
[PMID 22348646] Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
[PMID 22198471] Genetic variants at chromosome 9p21, 10p15 and 10q22 and breast cancer susceptibility in a Chinese population.
four common SNPs at 9p21(rs1011970 and rs10757278), 10p15 (rs2380205), and 10q22 (rs1250009) in a two-stage case-control study with a total of 1792 breast cancer cases and 1,867 controls. We found that rs1250009 at 10q22 was consistently associated with risk of breast cancer in stage 1 and stage 2, with a per-allele OR of 1.13 (95% CI 1.02-1.25) after two stages combined (P = 0.023). However, no significant associations were observed between the other three SNPs and breast cancer risk.
[PMID 22461340] 11q13 is a susceptibility locus for hormone receptor positive breast cancer
[PMID 22198471] in Chinese women no significant breast cancer association at rs1011970, rs10757278 or rs2380205
[PMID 26175953] FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population