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rs2413450

From SNPedia

Orientationplus
Stabilizedplus
Make rs2413450(C;C)
Make rs2413450(C;T)
Make rs2413450(T;T)
ReferenceGRCh38 38.1/141
Chromosome22
Position37074184
GeneTMPRSS6
is asnp
is mentioned by
dbSNPrs2413450
ebirs2413450
HLIrs2413450
Exacrs2413450
Varsomers2413450
Maprs2413450
PheGenIrs2413450
hapmaprs2413450
1000 genomesrs2413450
hgdprs2413450
ensemblrs2413450
gopubmedrs2413450
geneviewrs2413450
scholarrs2413450
googlers2413450
pharmgkbrs2413450
gwascentralrs2413450
openSNPrs2413450
23andMers2413450
23andMe allrs2413450
SNP Nexus

SNPshotrs2413450
SNPdbers2413450
MSV3drs2413450
GWAS Ctlgrs2413450
GMAF0.4265
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19862010OA-icon.png]
Trait Hematocrit
Title Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
Risk Allele T
P-val 2E-13
Odds Ratio 0.17 [0.13-0.22] % decrease


GET Evidence
rs2413450
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.546875
summary



GWAS snp
PMID [PMID 23935956OA-icon.png]
Trait Red blood cell traits
Title Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.
Risk Allele T
P-val 4E-7
Odds Ratio .01 [0.0060-0.0138] unit decrease
GWAS snp
PMID [PMID 20139978]
Trait Hematological and biochemical traits
Title Genome-wide association study of hematological and biochemical traits in a Japanese population.
Risk Allele T
P-val 5E-6
Odds Ratio .20 [0.116-0.291] unit decrease