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rs2437896

From SNPedia

Orientationplus
Stabilizedplus
Make rs2437896(C;C)
Make rs2437896(C;T)
Make rs2437896(T;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position175457761
is asnp
is mentioned by
dbSNPrs2437896
ebirs2437896
HLIrs2437896
Exacrs2437896
Varsomers2437896
Maprs2437896
PheGenIrs2437896
hapmaprs2437896
1000 genomesrs2437896
hgdprs2437896
ensemblrs2437896
gopubmedrs2437896
geneviewrs2437896
scholarrs2437896
googlers2437896
pharmgkbrs2437896
gwascentralrs2437896
openSNPrs2437896
23andMers2437896
23andMe allrs2437896
SNP Nexus

SNPshotrs2437896
SNPdbers2437896
MSV3drs2437896
GWAS Ctlgrs2437896
GMAF0.4692
Max Magnitude
? (C;C) (C;T) (T;T) 28
This SNP was identified as a "core" SNP helping to define one (of nine total) runs of homozygosity (ROH) potentially associated with increased risk for schizophrenia. Each region consists of at least 100 consecutive SNPs, generally spanning 500KB or more, for which both chromosomes in an individual were homozygous. The overall odds ratio for schizophrenia associated with inheriting 1, 2, or 3 of these 9 ROHs was calculated to be 3.3, 5.4, or 24, respectively, with 95% confidence intervals of (1.9-5.7), (3.7-16.1), and (6.9-83.9), respectively.[PMID 18077426OA-icon.png]

This particular SNP, rs2437896, was deemed to be the core SNP of a region on chromosome 2 with 115 SNPs spanning 774KB from 2:175671012 to 2:176445047 (build 35). Potentially independent of the ROH, the risk allele for this SNP in the orientation as displayed in HapMap v21a is (T).[PMID 18077426OA-icon.png]