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rs244715

From SNPedia

Orientationminus
Stabilizedplus
Make rs244715(C;C)
Make rs244715(C;T)
Make rs244715(T;T)
ReferenceGRCh38 38.1/142
Chromosome5
Position177076562
is asnp
is mentioned by
dbSNPrs244715
ebirs244715
HLIrs244715
Exacrs244715
Varsomers244715
Maprs244715
PheGenIrs244715
hapmaprs244715
1000 genomesrs244715
hgdprs244715
ensemblrs244715
gopubmedrs244715
geneviewrs244715
scholarrs244715
googlers244715
pharmgkbrs244715
gwascentralrs244715
openSNPrs244715
23andMers244715
23andMe allrs244715
SNP Nexus

SNPshotrs244715
SNPdbers244715
MSV3drs244715
GWAS Ctlgrs244715
GMAF0.4008
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs244715 is a SNP on chromosome 5.

A case control study of ~2,000 women found that each rs244715(T) allele was associated with an average increase in age at menopause of ~1 month. This also meant that each rs244715(C) allele yielded an odds ratio of 1.2 (CI: 1.09–1.32, p = 1.7 x 10e-4) of early menopause, defined as occurring before the age of 46.[PMID 20952801OA-icon.png]

Overall, women homozygous for the "early" alleles at all 4 SNPs found in this study were ~4 times more likely to undergo menopause early compared to women who had a total of 3 or less risk alleles. However, the ability to predict which women will actually undergo early menopause using these 4 SNPs is still low.[PMID 20952801OA-icon.png]