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rs2523608

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0 common in clinvar
Make rs2523608(C;T)
Make rs2523608(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position31354782
GeneHLA-B, MIR6891
is asnp
is mentioned by
dbSNPrs2523608
ebirs2523608
HLIrs2523608
Exacrs2523608
Varsomers2523608
Maprs2523608
PheGenIrs2523608
hapmaprs2523608
1000 genomesrs2523608
hgdprs2523608
ensemblrs2523608
gopubmedrs2523608
geneviewrs2523608
scholarrs2523608
googlers2523608
pharmgkbrs2523608
gwascentralrs2523608
openSNPrs2523608
23andMers2523608
23andMe allrs2523608
SNP Nexus

SNPshotrs2523608
SNPdbers2523608
MSV3drs2523608
GWAS Ctlgrs2523608
GMAF0.421
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 20205591OA-icon.png]
Trait HIV-1 control
Title Host determinants of HIV-1 control in African Americans
Risk Allele
P-val 0.000003
Odds Ratio None None


GWAS snp
PMID [PMID 21051598OA-icon.png]
Trait
Title The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation
Risk Allele G
P-val 9E-20
Odds Ratio 2.6000 [NR]


ClinVar
Risk rs2523608(T;T)
Alt rs2523608(T;T)
Reference rs2523608(C;C)
Significance Histocompatibility
Disease
Variation info
Gene HLA-B
CLNDBN
Reversed 1
HGVS NC_000006.11:g.31322559G>A
CLNSRC
CLNACC



[PMID 20018067OA-icon.png] A two-stage search strategy for detecting multiple loci associated with rheumatoid arthritis.


[PMID 22474614OA-icon.png] Host Genes Important to HIV Replication and Evolution.


GET Evidence
rs2523608
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.595238
summary



GWAS snp
PMID [PMID 23417110OA-icon.png]
Trait Beta-2 microglubulin plasma levels
Title Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.
Risk Allele A
P-val 9E-9
Odds Ratio .02 [0.012-0.028] unit increase