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rs2546890

From SNPedia

Associated with multiple sclerosis
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1 Higher risk of multiple sclerosis
(A;G) 1 Higher risk of multiple sclerosis
(G;G) 1 Lower risk of multiple sclerosis
ReferenceGRCh38 38.1/141
Chromosome5
Position159332892
GeneFBXO44
is asnp
is mentioned by
dbSNPrs2546890
ebirs2546890
HLIrs2546890
Exacrs2546890
Varsomers2546890
Maprs2546890
PheGenIrs2546890
hapmaprs2546890
1000 genomesrs2546890
hgdprs2546890
ensemblrs2546890
gopubmedrs2546890
geneviewrs2546890
scholarrs2546890
googlers2546890
pharmgkbrs2546890
gwascentralrs2546890
openSNPrs2546890
23andMers2546890
23andMe allrs2546890
SNP Nexus

SNPshotrs2546890
SNPdbers2546890
MSV3drs2546890
GWAS Ctlgrs2546890
GMAF0.4334
Max Magnitude1
? (A;A) (A;G) (G;G) 28

23andMe blog multiple sclerosis rs2546890 IL12B G 0.87

GWAS snp
PMID [PMID 20953188OA-icon.png]
Trait
Title Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
Risk Allele A
P-val 1E-20
Odds Ratio 1.5400 [1.32-1.79] (Panel A)
GWAS snp
PMID [PMID 22190364OA-icon.png]
Trait
Title Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
Risk Allele A
P-val 8E-8
Odds Ratio 1.1600 None
GWAS snp
PMID [PMID 21833088OA-icon.png]
Trait
Title Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Risk Allele A
P-val 1E-11
Odds Ratio 1.1100 [1.10-1.13]


[PMID 16600026OA-icon.png] Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway.


[PMID 19956101OA-icon.png] Overview of the Rapid Response data.


[PMID 19956104OA-icon.png] Evaluation of IL12B as a candidate type I diabetes susceptibility gene using data from the Type I Diabetes Genetics Consortium.


[PMID 23785401OA-icon.png] Association of Genetic Markers with CSF Oligoclonal Bands in Multiple Sclerosis Patients