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rs2606345

From SNPedia

Orientationplus
Stabilizedplus
Make rs2606345(A;A)
Make rs2606345(A;C)
Make rs2606345(C;C)
ReferenceGRCh38 38.1/141
Chromosome15
Position74724835
GeneCYP1A1
is asnp
is mentioned by
dbSNPrs2606345
ebirs2606345
HLIrs2606345
Exacrs2606345
Varsomers2606345
Maprs2606345
PheGenIrs2606345
hapmaprs2606345
1000 genomesrs2606345
hgdprs2606345
ensemblrs2606345
gopubmedrs2606345
geneviewrs2606345
scholarrs2606345
googlers2606345
pharmgkbrs2606345
gwascentralrs2606345
openSNPrs2606345
23andMers2606345
23andMe allrs2606345
SNP Nexus

SNPshotrs2606345
SNPdbers2606345
MSV3drs2606345
GWAS Ctlgrs2606345
GMAF0.3352
Max Magnitude
[PMID 18415690] 577 testicular germ cell tumors cases (254 seminoma, 323 nonseminoma) and 707 controls.

inversely associated with nonseminoma:

  • rs4886605 OR = 0.75 (95% CI = 0.54-1.04) among the heterozygotes and OR = 0.37, 95% CI = 0.12-1.11 among the homozygotes with a p-value for trend = 0.02;
  • rs2606345 OR = 0.69 (95% CI = 0.51-0.93) among heterozygotes and OR = 0.70 (95% CI = 0.42-1.17) among homozygotes, with a p-value for trend = 0.02.


[PMID 19168589OA-icon.png] Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China

[PMID 19479063OA-icon.png] Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression


[PMID 19630952OA-icon.png] Sex steroid metabolism polymorphisms and mammographic density in pre- and early peri-menopausal women


[PMID 16949383] Sex steroid hormone pathway genes and health-related measures in women of 4 races/ethnicities: the Study of Women's Health Across the Nation (SWAN).


[PMID 16949388] CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal.


[PMID 16949389] Vasomotor symptom prevalence is associated with polymorphisms in sex steroid-metabolizing enzymes and receptors.


[PMID 16949393] Sex steroid hormone gene polymorphisms and depressive symptoms in women at midlife.


[PMID 18268125OA-icon.png] Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns.


[PMID 18579753OA-icon.png] Vascular actions of estrogens: functional implications.


[PMID 18632753OA-icon.png] Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.


[PMID 18691756OA-icon.png] Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk.


[PMID 18936436OA-icon.png] Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.


[PMID 19330903OA-icon.png] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.


[PMID 22569204OA-icon.png] PharmGKB summary: phenytoin pathway.


[PMID 23411129] Functional polymorphisms in the CYP1A1, ACE, and IL-6 genes contribute to susceptibility to community-acquired and nosocomial pneumonia


[PMID 23107763] Host genetic risk factors for community-acquired pneumonia.


[PMID 23661361] The potential effect of gender in CYP1A1 and GSTM1 genotype-specific associations with pediatric brain tumor.


[PMID 24068433] CYP1A1, GCLC, AGT, AGTR1 gene-gene interactions in community-acquired pneumonia pulmonary complications