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rs261332

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 associated with higher HDL cholesterol
(A;G) 2 associated with higher HDL cholesterol
(G;G) 0 common in complete genomics
ReferenceGRCh38 38.1/141
Chromosome15
Position58435126
GeneLIPC, RP11-355N15.1
is asnp
is mentioned by
dbSNPrs261332
ebirs261332
HLIrs261332
Exacrs261332
Varsomers261332
Maprs261332
PheGenIrs261332
hapmaprs261332
1000 genomesrs261332
hgdprs261332
ensemblrs261332
gopubmedrs261332
geneviewrs261332
scholarrs261332
googlers261332
pharmgkbrs261332
gwascentralrs261332
openSNPrs261332
23andMers261332
23andMe allrs261332
SNP Nexus

SNPshotrs261332
SNPdbers261332
MSV3drs261332
GWAS Ctlgrs261332
GMAF0.1924
Max Magnitude2
? (A;A) (A;G) (G;G) 28
Rs261332
PubMed [PMID 17463246]
Affy Probeset SNP_A-4301630
Affy Orientation reverse
On GW 5.0 1
Alleles A/B C/T
Ancestral
Population NEU
Allele A
Case Freq.
Control Freq. 0.18
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All -
Disease Elevated HDL-Cholesterol (E-HDL)


rs261332 increases susceptibility to Elevated HDL-Cholesterol for carriers of the A allele [PMID 17463246]

A allele is associated with 1.41mg/dl increase in HDL cholesterol (good cholesterol). [PMID 18193043]


[PMID 18179892OA-icon.png] Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.


[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19101670OA-icon.png] LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion.


[PMID 21283740OA-icon.png] Large-scale candidate gene analysis of HDL particle features.