|| common in complete genomics
|?|| (C;C) (C;G) (G;G) ||28|
[PMID 18487243] People with the C version of rs2630578(C) have telomeres in their white blood cells that are between 400 and 800 base pairs shorter than people with two copies of the other version of this SNP. The authors estimate that this is the equivalent of having cells that are comparatively about 15 to 20 years older, though no actual effects on aging or health were associated with this SNP in the study.
(While rs2630578 is not in 23andMeâ€™s database, customers can check their data using the direct substitute rs2668301. The T version of rs2668301 is equivalent to having the C version of rs2630578.)
[PMID 20127402] Cerebellar telomere length and psychiatric disorders
[PMID 22314626] Genetic variants implicated in telomere length associated with left ventricular function in patients with hypertension and cardiac organ damage
[PMID 24349443] Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease
[PMID 25792135] hTERT, BICD1 and Chromosome 18 Polymorphisms Associated with Telomere Length Affect Kidney Allograft Function After Transplantation