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rs2648875

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 8.82x increased risk of ESRD in diabetes type II patients
(A;G) 2.97x increased risk of ESRD in diabetes type II patients
(G;G) normal
ReferenceGRCh38 38.1/141
Chromosome8
Position128059915
GenePVT1
is asnp
is mentioned by
dbSNPrs2648875
ebirs2648875
HLIrs2648875
Exacrs2648875
Varsomers2648875
Maprs2648875
PheGenIrs2648875
hapmaprs2648875
1000 genomesrs2648875
hgdprs2648875
ensemblrs2648875
gopubmedrs2648875
geneviewrs2648875
scholarrs2648875
googlers2648875
pharmgkbrs2648875
gwascentralrs2648875
openSNPrs2648875
23andMers2648875
23andMe allrs2648875
SNP Nexus

SNPshotrs2648875
SNPdbers2648875
MSV3drs2648875
GWAS Ctlgrs2648875
GMAF0.4132
Max Magnitude
? (A;A) (A;G) (G;G) 28

Study of 105 unrelated case subjects with ESRD and 102 controls with type 2 diabetes for > or =10 years without macroalbuminuria. Association observed for rs2648875 (OR 2.97 per A allele) [1]

GWAS
SNP rs2648875
PubMedID [PMID 17395743]
Condition End-stage renal disease
Gene PVT1
Risk Allele A
pValue 2.00E-006
OR 2.97
95% CI 1.90-4.65



GET Evidence
rs2648875
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.359375
summary