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rs2660753

From SNPedia

Orientationplus
Stabilizedplus
Make rs2660753(C;C)
Make rs2660753(C;T)
Make rs2660753(T;T)
ReferenceGRCh38 38.1/141
Chromosome3
Position87061524
is asnp
is mentioned by
dbSNPrs2660753
ebirs2660753
HLIrs2660753
Exacrs2660753
Varsomers2660753
Maprs2660753
PheGenIrs2660753
hapmaprs2660753
1000 genomesrs2660753
hgdprs2660753
ensemblrs2660753
gopubmedrs2660753
geneviewrs2660753
scholarrs2660753
googlers2660753
pharmgkbrs2660753
gwascentralrs2660753
openSNPrs2660753
23andMers2660753
23andMe allrs2660753
SNP Nexus

SNPshotrs2660753
SNPdbers2660753
MSV3drs2660753
GWAS Ctlgrs2660753
GMAF0.2681
Max Magnitude
? (C;C) (C;T) (T;T) 28
cancer-genetics these snps influence genetic risk for prostate cancer

[PMID 18708398OA-icon.png] rs2660753 showed a per-allele OR, 1.08 (95% confidence interval, 1.00-1.16; P = 0.06)

An initial report [PMID 18974127OA-icon.png] of an association with between this SNP and risk for ovarian cancer was not replicated when the same authors expanded the study over 12 studies comprising 4,482 cases (and over 6,000 controls).[PMID 21415361OA-icon.png]


[PMID 19336566OA-icon.png] Replication of the 10q11 and Xp11 Prostate Cancer Risk Variants: Results from a Utah Pedigree-Based Study.

GWAS snp
PMID [PMID 18264097]
Trait Prostate cancer
Title Multiple newly identified loci associated with prostate cancer susceptibility
Risk Allele T
P-val 2.9999999999999997E-8
Odds Ratio 1.18 [1.06-1.31]


[PMID 21898988] [Two single nucleotide polymorphisms on chromosome 3 and the risk of prostate cancer in Chinese men]


[PMID 22549899OA-icon.png] Genetic polymorphism and prostate cancer aggressiveness: A case-only study of 1,536 GWAS and candidate SNPs in African-Americans and European-Americans


[PMID 22733159] Analysis of prostate cancer association with four single-nucleotide polymorphisms from genome-wide studies and serum phyto-estrogen concentrations


[PMID 18794092OA-icon.png] Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.


[PMID 19104501OA-icon.png] Prostate cancer genomics: towards a new understanding.


[PMID 19318432OA-icon.png] Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.


[PMID 19366831OA-icon.png] Analysis of recently identified prostate cancer susceptibility loci in a population-based study: associations with family history and clinical features.


[PMID 19434657OA-icon.png] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.


[PMID 19549807OA-icon.png] Prostate cancer risk associated loci in African Americans.


[PMID 19639606OA-icon.png] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.


[PMID 20039378OA-icon.png] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.


[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.


[PMID 21390317OA-icon.png] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.


[PMID 21538423OA-icon.png] Early onset prostate cancer has a significant genetic component.


GET Evidence
rs2660753
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.648438
summary