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rs272893

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;G) 0 common in complete genomics
Make rs272893(A;A)
Make rs272893(G;G)
ReferenceGRCh38 38.1/141
Chromosome5
Position132327369
GeneLOC553103, SLC22A4
is asnp
is mentioned by
dbSNPrs272893
ebirs272893
HLIrs272893
Exacrs272893
Varsomers272893
Maprs272893
PheGenIrs272893
hapmaprs272893
1000 genomesrs272893
hgdprs272893
ensemblrs272893
gopubmedrs272893
geneviewrs272893
scholarrs272893
googlers272893
pharmgkbrs272893
gwascentralrs272893
openSNPrs272893
23andMers272893
23andMe allrs272893
SNP Nexus

SNPshotrs272893
SNPdbers272893
MSV3drs272893
GWAS Ctlgrs272893
GMAF0.4146
Max Magnitude0
? (A;A) (A;G) (G;G) 28
[PMID 18668679] rs272893 and rs273900 are associated with Crohn's disease (OR 2.16; 95% CI 1.21-3.59 and OR 2.40; 95% CI 1.43-4.05)


Venter snp
Source plos
Gene SLC22A4
allele C
frequency 0.342
sift TOLERATED
HuRef 1103654225921
Disease Association Defects in SLC22A4 may be a cause of rheumatoid arthritis (RA).



[PMID 16796743OA-icon.png] Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study.


[PMID 17476680] Genetic susceptibility has a more important role in pediatric-onset Crohn's disease than in adult-onset Crohn's disease.


GET Evidence
SLC22A4-I306T
aa_change Ile306Thr
aa_change_short I306T
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.658022
summary