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rs2794520

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;T) 0 common in complete genomics
Make rs2794520(C;C)
Make rs2794520(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position159709026
is asnp
is mentioned by
dbSNPrs2794520
ebirs2794520
HLIrs2794520
Exacrs2794520
Varsomers2794520
Maprs2794520
PheGenIrs2794520
hapmaprs2794520
1000 genomesrs2794520
hgdprs2794520
ensemblrs2794520
gopubmedrs2794520
geneviewrs2794520
scholarrs2794520
googlers2794520
pharmgkbrs2794520
gwascentralrs2794520
openSNPrs2794520
23andMers2794520
23andMe allrs2794520
SNP Nexus

SNPshotrs2794520
SNPdbers2794520
MSV3drs2794520
GWAS Ctlgrs2794520
GMAF0.3687
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS
SNP rs2794520
PubMedID [PMID 17903293OA-icon.png]
Condition Select biomarker traits
Gene CRP
Risk Allele
pValue 3.00E-008
OR NA
95% CI


[PMID 17903293OA-icon.png] select biomarker trait being C-reactive protein (CRP) levels

GWAS snp
PMID [PMID 19060910OA-icon.png]
Trait Other metabolic traits
Title Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
Risk Allele A
P-val 3E-22
Odds Ratio 0.47 [0.32-0.62] mmol/l decrease




GWAS snp
PMID [PMID 21300955OA-icon.png]
Trait
Title Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels
Risk Allele C
P-val 0
Odds Ratio 0.1600 [0.15-0.17] unit increase


[PMID 22230323] Pharmacogenetic Determinants of Statin-Induced Reductions in C-Reactive Protein


[PMID 17903291OA-icon.png] The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports.


[PMID 18216863OA-icon.png] Genetic determinants of basal C-reactive protein expression in Filipino systemic lupus erythematosus families.


[PMID 18439548OA-icon.png] Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.


[PMID 18500540OA-icon.png] Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach.


[PMID 19426506OA-icon.png] C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery.


GET Evidence
rs2794520
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.335938
summary



[PMID 23496329] Genetic variation in C-reactive protein in ethnic Chinese population in Taiwan.


[PMID 24862635] Association of CRP gene polymorphisms with serum CRP level and handgrip strength in community-dwelling elders in Taiwan: Taichung Community Health Study for Elders (TCHS-E)