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rs280523

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs280523(A;A)
Make rs280523(A;G)
ReferenceGRCh38 38.1/141
Chromosome19
Position10366530
GeneTYK2
is asnp
is mentioned by
dbSNPrs280523
ebirs280523
HLIrs280523
Exacrs280523
Varsomers280523
Maprs280523
PheGenIrs280523
hapmaprs280523
1000 genomesrs280523
hgdprs280523
ensemblrs280523
gopubmedrs280523
geneviewrs280523
scholarrs280523
googlers280523
pharmgkbrs280523
gwascentralrs280523
openSNPrs280523
23andMers280523
23andMe allrs280523
SNP Nexus

SNPshotrs280523
SNPdbers280523
MSV3drs280523
GWAS Ctlgrs280523
GMAF0.07805
Max Magnitude0
? (A;A) (A;G) (G;G) 28

[PMID 21140222] Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases


[PMID 15657875OA-icon.png] Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.


[PMID 19653082OA-icon.png] Strong evidence of a combination polymorphism of the tyrosine kinase 2 gene and the signal transducer and activator of transcription 3 gene as a DNA-based biomarker for susceptibility to Crohn's disease in the Japanese population.


[PMID 23000200] TYK2 rs34536443 polymorphism is associated with a decreased susceptibility to endometriosis-related infertility.


ClinVar
Risk rs280523(A,C;A,C)
Alt rs280523(A,C;A,C)
Reference rs280523(G;G)
Significance Non-pathogenic
Disease not specified
Variation info
Gene TYK2
CLNDBN not specified
Reversed 0
HGVS NC_000019.9:g.10477206G>A
CLNSRC ClinVar GeneDx
CLNACC RCV000126189.1,



[PMID 25744728] Tyrosine kinase-2 gene polymorphisms are associated with ulcerative colitis and Crohn's disease in Turkish Population