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rs2812378

From SNPedia

Orientationminus
Stabilizedminus
Make rs2812378(C;C)
Make rs2812378(C;T)
Make rs2812378(T;T)
ReferenceGRCh38 38.1/141
Chromosome9
Position34710263
GeneCCL21, LOC101929761
is asnp
is mentioned by
dbSNPrs2812378
ebirs2812378
HLIrs2812378
Exacrs2812378
Varsomers2812378
Maprs2812378
PheGenIrs2812378
hapmaprs2812378
1000 genomesrs2812378
hgdprs2812378
ensemblrs2812378
gopubmedrs2812378
geneviewrs2812378
scholarrs2812378
googlers2812378
pharmgkbrs2812378
gwascentralrs2812378
openSNPrs2812378
23andMers2812378
23andMe allrs2812378
SNP Nexus

SNPshotrs2812378
SNPdbers2812378
MSV3drs2812378
GWAS Ctlgrs2812378
GMAF0.2801
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS
SNP rs2812378
PubMedID [PMID 18794853OA-icon.png]
Condition Rheumatoid arthritis
Gene CCL21
Risk Allele G
pValue 3.00E-008
OR 1.12
95% CI


OMIM180300
DescRHEUMATOID ARTHRITIS; RA
Variant
Relatedalso
[PMID 20461788OA-icon.png] Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients

[PMID 19180477OA-icon.png] Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations.

[PMID 19435719OA-icon.png] Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.

[PMID 19674979OA-icon.png] Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.

[PMID 20439292] Genetic variants in the prediction of rheumatoid arthritis.

[PMID 20444755OA-icon.png] Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.

[PMID 20797713] Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1.


[PMID 23007924] Association of Rheumatoid Arthritis Risk Alleles with Response to Anti-TNF Biologics: Results from the CORRONA Registry and Meta-analysis


GET Evidence
rs2812378
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.726562
summary



[PMID 22328738OA-icon.png] Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.