|| >1.2x increased risk for ALS
|| 1.2x increased risk for ALS
|?|| (A;A) (A;G) (G;G) ||28|
is one of 2 SNPs from the ch 9p21.2 region associated in a large GWAS study with ALS
risk, the other SNP being rs3849942
. In this study, the reported odds ratio for rs2814707
(A) was 1.22 (CI: 1.15 - 1.30, p = 4.72 x 10e-10).[PMID 20801717
The odds ratio for the minor rs2814707(A) allele was 1.16 (p=7.45x10e-9).[PMID 19734901]
23andMe blog rs2814707(T) 1.16x odds of ALS
rs12608932(C) 1.2x odds of ALS
] Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study.
[PMID 20706608] The role of genetic variation near interferon-kappa in systemic lupus erythematosus.
[PMID 21295378] Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
|| Insufficiently evaluated pathogenic