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rs2815752

From SNPedia

Orientationminus
Stabilizedminus
Make rs2815752(C;C)
Make rs2815752(C;T)
Make rs2815752(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position72346757
is asnp
is mentioned by
dbSNPrs2815752
ebirs2815752
HLIrs2815752
Exacrs2815752
Varsomers2815752
Maprs2815752
PheGenIrs2815752
hapmaprs2815752
1000 genomesrs2815752
hgdprs2815752
ensemblrs2815752
gopubmedrs2815752
geneviewrs2815752
scholarrs2815752
googlers2815752
pharmgkbrs2815752
gwascentralrs2815752
openSNPrs2815752
23andMers2815752
23andMe allrs2815752
SNP Nexus

SNPshotrs2815752
SNPdbers2815752
MSV3drs2815752
GWAS Ctlgrs2815752
GMAF0.3007
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 19164386OA-icon.png] obesity and type-2 diabetes
GWAS snp
PMID [PMID 19079261OA-icon.png]
Trait Body mass index
Title Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
Risk Allele A
P-val 6E-8
Odds Ratio 0.10 [0.04-0.16] kg/m2 increase


GWAS snp
PMID [PMID 20935630OA-icon.png]
Trait
Title Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Risk Allele A
P-val 2E-22
Odds Ratio 0.13 [0.09-0.17] kg/m2 increase
OMIM601665
Desc
Variant
Relatedalso


[PMID 21796141] Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area


[PMID 22083549] Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty

[PMID 19526209OA-icon.png] Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

[PMID 19553259OA-icon.png] Common body mass index-associated variants confer risk of extreme obesity.

[PMID 19910938] Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.

[PMID 20127379OA-icon.png] From monogenic to polygenic obesity: recent advances.

[PMID 20144318OA-icon.png] A strategy for analyzing gene-nutrient interactions in type 2 diabetes.

[PMID 20712903OA-icon.png] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.

[PMID 21283731OA-icon.png] FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome.

[PMID 22179955OA-icon.png] Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program.


GET Evidence
rs2815752
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.648438
summary



[PMID 23431394OA-icon.png] Rs4074134 near BDNF gene is associated with type 2 diabetes mellitus in chinese han population independently of body mass index


[PMID 23950990OA-icon.png] Contribution of 32 GWAS-Identified Common Variants to Severe Obesity in European Adults Referred for Bariatric Surgery


[PMID 23471855OA-icon.png] The genetics of childhood obesity and interaction with dietary macronutrients.


[PMID 25072390OA-icon.png] Obesity Gene NEGR1 Associated with White Matter Integrity in Healthy Young Adults