| 2.67x increased risk for systemic sclerosis |
| Geno
|
Mag
|
Summary
|
| (A;A)
|
2.1
|
2.67x increased risk for systemic sclerosis
|
| (A;G)
|
0
|
normal
|
| (G;G)
|
0
|
normal
|
[PMID 24819332] IL-10RB rs2834167 (A/G) polymorphism is associated with the susceptibility to systemic lupus erythematosus: evidence from a study in Chinese Han population.
We found that the frequency of A allele for rs2834167 in patients (44.53 %) was significantly higher than in controls (40.16 %) (χ (2) = 5.24, P = 0.022). Allele A was associated with a 1.196-fold (95 % confidence interval (CI), 1.026-1.394) greater risk for the occurrence of SLE compared with the G allele. And both genotypes AG and AA were associated with the susceptibility to SLE as compared with the GG genotype (AG versus GG, odds ratio (OR) = 1.332; 95 %CI, 1.047-1.696; AA versus GG, OR = 1.373; 95 %CI, 1.004-1.878).
