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rs2836878

From SNPedia

Orientationplus
Stabilizedplus
Make rs2836878(A;A)
Make rs2836878(A;G)
Make rs2836878(G;G)
ReferenceGRCh38 38.1/141
Chromosome21
Position39093608
is asnp
is mentioned by
dbSNPrs2836878
ebirs2836878
HLIrs2836878
Exacrs2836878
Varsomers2836878
Maprs2836878
PheGenIrs2836878
hapmaprs2836878
1000 genomesrs2836878
hgdprs2836878
ensemblrs2836878
gopubmedrs2836878
geneviewrs2836878
scholarrs2836878
googlers2836878
pharmgkbrs2836878
gwascentralrs2836878
openSNPrs2836878
23andMers2836878
23andMe allrs2836878
SNP Nexus

SNPshotrs2836878
SNPdbers2836878
MSV3drs2836878
GWAS Ctlgrs2836878
GMAF0.2185
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS
SNP rs2836878
PubMedID [PMID 18758464OA-icon.png]
Condition Inflammatory bowel disease
Gene PSMG1
Risk Allele
pValue 4.00E-012
OR 1.41
95% CI 1.08-1.84


OMIM612567
DescINFLAMMATORY BOWEL DISEASE 25; IBD25
Variant
Relatedalso


GWAS snp
PMID [PMID 21300955OA-icon.png]
Trait
Title Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels
Risk Allele G
P-val 2E-7
Odds Ratio 0.0320 [0.02-0.04] unit increase
GWAS snp
PMID [PMID 21297633OA-icon.png]
Trait
Title Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Risk Allele G
P-val 2E-22
Odds Ratio 1.2500 [1.20-1.32]


[PMID 19623168] Investigation of reported associations between the 20q13 and 21q22 loci and pediatric-onset Crohn's disease in Canadian children.


[PMID 21304977OA-icon.png] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.


GET Evidence
rs2836878
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.21875
summary Associated with Inflammatory bowel disease, Chron's disease.



GWAS snp
PMID [PMID 23128233OA-icon.png]
Trait Inflammatory bowel disease
Title Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Risk Allele G
P-val 5E-48
Odds Ratio 1.18 [1.142-1.219]