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rs28371725

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) CYP2D6*41 homozygote
(A;G) carrier of one CYP2D6*41 allele
(G;G) 0 normal
ReferenceGRCh37 37.1/131
Chromosome22
Position42523805
GeneCYP2D6
is asnp
is mentioned by
dbSNPrs28371725
ebirs28371725
HLIrs28371725
Exacrs28371725
Varsomers28371725
Maprs28371725
PheGenIrs28371725
hapmaprs28371725
1000 genomesrs28371725
hgdprs28371725
ensemblrs28371725
gopubmedrs28371725
geneviewrs28371725
scholarrs28371725
googlers28371725
pharmgkbrs28371725
gwascentralrs28371725
openSNPrs28371725
23andMers28371725
23andMe allrs28371725
SNP Nexus

SNPshotrs28371725
SNPdbers28371725
MSV3drs28371725
GWAS Ctlgrs28371725
GMAF0.05556
Max Magnitude0

rs28371725, also known as 2988G>A, is a SNP in the CYP2D6 gene.

The rs28371725(A) allele defines the CYP2D6*41 variant, which has decreased activity.

23andMe also has SNP i4001476 at the same position.




[PMID 22448283OA-icon.png] Genotyping Performance between Saliva and Blood-Derived Genomic DNAs on the DMET Array: A Comparison


[PMID 20174590OA-icon.png] Response to serotonin reuptake inhibitors in OCD is not influenced by common CYP2D6 polymorphisms.


[PMID 21071160] Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population.


GET Evidence
rs28371725
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.078815
summary