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rs2853676

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 0
Make rs2853676(A;A)
Make rs2853676(A;G)
ReferenceGRCh38 38.1/141
Chromosome5
Position1288432
GeneTERT
is asnp
is mentioned by
dbSNPrs2853676
ebirs2853676
HLIrs2853676
Exacrs2853676
Varsomers2853676
Maprs2853676
PheGenIrs2853676
hapmaprs2853676
1000 genomesrs2853676
hgdprs2853676
ensemblrs2853676
gopubmedrs2853676
geneviewrs2853676
scholarrs2853676
googlers2853676
pharmgkbrs2853676
gwascentralrs2853676
openSNPrs2853676
23andMers2853676
23andMe allrs2853676
SNP Nexus

SNPshotrs2853676
SNPdbers2853676
MSV3drs2853676
GWAS Ctlgrs2853676
GMAF0.2305
Max Magnitude0
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19578367OA-icon.png]
Trait Glioma
Title Genome-wide association study identifies five susceptibility loci for glioma
Risk Allele A
P-val 4E-14
Odds Ratio 1.26 [1.20-1.32]


[PMID 22495810] Association of genetic variants of human telomerase with colorectal polyps and colorectal cancer risk


[PMID 22795327] Selected polymorphisms of GSTP1 and TERT were associated with glioma risk in Han Chinese


[PMID 19836008OA-icon.png] A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.


[PMID 21116649OA-icon.png] Genetic variants in telomere-maintaining genes and skin cancer risk.


[PMID 22267287OA-icon.png] Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk.


[PMID 22539396] hTERT cancer risk genotypes are associated with telomere length.


GET Evidence
rs2853676
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.696721
summary



[PMID 23535824OA-icon.png] Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.


[PMID 23812731] RTEL1 and TERT polymorphisms are associated with astrocytoma risk in the Chinese Han population.


[PMID 26042809OA-icon.png] Association between the TERT Genetic Polymorphism rs2853676 and Cancer Risk: Meta-Analysis of 76 108 Cases and 134 215 Controls


[PMID 26320593] A single-nucleotide polymorphism of CCL21 rs951005 T>C is associated with susceptibility of polymyositis and such patients with interstitial lung disease in a Chinese Han population.


[PMID 27825130] Genetic variants in TERT are associated with risk of gastric cancer in a Chinese Han population.