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rs2853677

From SNPedia

Orientationminus
Stabilizedplus
Make rs2853677(C;C)
Make rs2853677(C;T)
Make rs2853677(T;T)
ReferenceGRCh38 38.1/142
Chromosome5
Position1287079
GeneTERT
is asnp
is mentioned by
dbSNPrs2853677
ebirs2853677
HLIrs2853677
Exacrs2853677
Varsomers2853677
Maprs2853677
PheGenIrs2853677
hapmaprs2853677
1000 genomesrs2853677
hgdprs2853677
ensemblrs2853677
gopubmedrs2853677
geneviewrs2853677
scholarrs2853677
googlers2853677
pharmgkbrs2853677
gwascentralrs2853677
openSNPrs2853677
23andMers2853677
23andMe allrs2853677
SNP Nexus

SNPshotrs2853677
SNPdbers2853677
MSV3drs2853677
GWAS Ctlgrs2853677
GMAF0.3512
Max Magnitude
? (C;C) (C;T) (T;T) 28

[PMID 22213090] Fine-mapping of a region of chromosome 5p15.33 (TERT-CLPTM1L) suggests a novel locus in TERT and a CLPTM1L haplotype are associated with glioma susceptibility in a Chinese population

GWAS snp
PMID [PMID 22797724]
Trait Lung adenocarcinoma
Title A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
Risk Allele C
P-val 3E-40
Odds Ratio 1.41 [1.32-1.50]


[PMID 20445798OA-icon.png] Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women.


[PMID 22539396] hTERT cancer risk genotypes are associated with telomere length.


[PMID 25027329] Imputation and subset based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33


[PMID 26294352] Association of human telomerase reverse transcriptase gene polymorphisms, serum levels, and telomere length with renal cell carcinoma risk and pathology


[PMID 27191258] Rs2853677 modulates Snail1 binding to the TERT enhancer and affects lung adenocarcinoma susceptibility.