|?|| (C;C) (C;T) (T;T) ||28|
] Fine-mapping of a region of chromosome 5p15.33 (TERT-CLPTM1L) suggests a novel locus in TERT and a CLPTM1L haplotype are associated with glioma susceptibility in a Chinese population
|| [PMID 22797724]
|| Lung adenocarcinoma
|| A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
| Risk Allele
| Odds Ratio
|| 1.41 [1.32-1.50]
[PMID 20445798] Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women.
[PMID 22539396] hTERT cancer risk genotypes are associated with telomere length.
[PMID 25027329] Imputation and subset based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
[PMID 26294352] Association of human telomerase reverse transcriptase gene polymorphisms, serum levels, and telomere length with renal cell carcinoma risk and pathology
[PMID 27191258] Rs2853677 modulates Snail1 binding to the TERT enhancer and affects lung adenocarcinoma susceptibility.