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rs2854344

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A)
(A;G)
(G;G) 0
ReferenceGRCh38 38.1/141
Chromosome13
Position48423557
GeneLPAR6, RB1
is asnp
is mentioned by
dbSNPrs2854344
ebirs2854344
HLIrs2854344
Exacrs2854344
Varsomers2854344
Maprs2854344
PheGenIrs2854344
hapmaprs2854344
1000 genomesrs2854344
hgdprs2854344
ensemblrs2854344
gopubmedrs2854344
geneviewrs2854344
scholarrs2854344
googlers2854344
pharmgkbrs2854344
gwascentralrs2854344
openSNPrs2854344
23andMers2854344
23andMe allrs2854344
SNP Nexus

SNPshotrs2854344
SNPdbers2854344
MSV3drs2854344
GWAS Ctlgrs2854344
GMAF0.02204
Max Magnitude0
? (A;A) (A;G) (G;G) 28
associated with breast cancer risk [PMID 16685266OA-icon.png] and ovarian cancer [PMID 17047088]

More specifically: carriers of two rs2854344(A) alleles have a 25% reduced risk of developing ovarian cancer compared to carriers of two rs2854344(G) alleles, in a survey of ~5,000 women from the US, UK, and Denmark. [PMID 17047088]

[PMID 18431743OA-icon.png] showed no association with ovarian cancer risk 4,624 invasive epithelial ovarian cancer cases and 8,113 controls of white non-Hispanic origin ovarian cancer


[PMID 18174243OA-icon.png] Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.


[PMID 18281541OA-icon.png] Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.


[PMID 19124506OA-icon.png] Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.


[PMID 19258477OA-icon.png] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.


[PMID 21641967] Genetic susceptibility to sporadic ovarian cancer: A systematic review.