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rs2854746

From SNPedia

Orientationminus
Stabilizedminus
Make rs2854746(C;C)
Make rs2854746(C;G)
Make rs2854746(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position45921046
GeneIGFBP3
is asnp
is mentioned by
dbSNPrs2854746
ebirs2854746
HLIrs2854746
Exacrs2854746
Varsomers2854746
Maprs2854746
PheGenIrs2854746
hapmaprs2854746
1000 genomesrs2854746
hgdprs2854746
ensemblrs2854746
gopubmedrs2854746
geneviewrs2854746
scholarrs2854746
googlers2854746
pharmgkbrs2854746
gwascentralrs2854746
openSNPrs2854746
23andMers2854746
23andMe allrs2854746
SNP Nexus

SNPshotrs2854746
SNPdbers2854746
MSV3drs2854746
GWAS Ctlgrs2854746
GMAF0.4826
Max Magnitude

[PMID 19240240OA-icon.png] IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women

[PMID 19551864OA-icon.png] Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease

OMIM146732
DescINSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3; IGFBP3
Variant
Relatedalso

[PMID 19784788] Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk

[PMID 19858071OA-icon.png] Common Genetic Variation in IGF1, IGFBP1, and IGFBP3 and Ovarian Cancer Risk

[PMID 20484221OA-icon.png] A Comprehensive Analysis of Common IGF1, IGFBP1 and IGFBP3 Genetic Variation with Prospective IGF-I and IGFBP-3 Blood Levels and Prostate Cancer Risk Among Caucasians


[PMID 21562710] Genotypes and phenotypes of IGF-I and IGFBP-3 in breast tumors among Chinese women

[PMID 17300730OA-icon.png] Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study.

[PMID 17566087] Genetic determinants of circulating insulin-like growth factor (IGF)-I, IGF binding protein (BP)-1, and IGFBP-3 levels in a multiethnic population.

[PMID 18031946] Polymorphisms in the insulin like growth factor 1 and IGF binding protein 3 genes and risk of colorectal cancer.

[PMID 18398040OA-icon.png] Transcription factor 7-like 2 polymorphism and colon cancer.

[PMID 18596909OA-icon.png] IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).

[PMID 18992263OA-icon.png] Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

[PMID 19938081OA-icon.png] Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.

[PMID 22354904OA-icon.png] Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study.


GET Evidence
IGFBP3-A32G
aa_change Ala32Gly
aa_change_short A32G
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.259651
summary



[PMID 27755861] Association of EGF, IGFBP-3 and TP53 Gene Polymorphisms with Major Depressive Disorder in Slovak Population.