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rs2891168

From SNPedia

Orientationplus
Stabilizedplus
Make rs2891168(A;A)
Make rs2891168(A;G)
Make rs2891168(G;G)
ReferenceGRCh38 38.1/141
Chromosome9
Position22098620
GeneCDKN2B-AS1
is asnp
is mentioned by
dbSNPrs2891168
ebirs2891168
HLIrs2891168
Exacrs2891168
Varsomers2891168
Maprs2891168
PheGenIrs2891168
hapmaprs2891168
1000 genomesrs2891168
hgdprs2891168
ensemblrs2891168
gopubmedrs2891168
geneviewrs2891168
scholarrs2891168
googlers2891168
pharmgkbrs2891168
gwascentralrs2891168
openSNPrs2891168
23andMers2891168
23andMe allrs2891168
SNP Nexus

SNPshotrs2891168
SNPdbers2891168
MSV3drs2891168
GWAS Ctlgrs2891168
GMAF0.4201
Max Magnitude
? (A;A) (A;G) (G;G) 28
Rs2891168
PubMed [PMID 17478681OA-icon.png]
Affy Probeset SNP_A-2150146
Affy Orientation same
On GW 5.0 1
Alleles A/B A/G
Ancestral A
Population CEU
Allele G
Case Freq.
Control Freq.
Odds Ratio Het 1.30
Odds Ratio Hom 1.54
Odds Ratio All 1.23
Disease Coronary artery disease (CAD)


Neighborrs4977574
Distance45

rs2891168 increases susceptibility to Coronary artery disease 1.30 times for heterozygotes (AG) and 1.54 times for homozygotes (GG) [PMID 18048406]


[PMID 19463184OA-icon.png] Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease


[PMID 20696043OA-icon.png] Replication of the association of chromosomal region 9p21.3 with generalized aggressive periodontitis (gAgP) using an independent case-control cohort

OMIM170650
Desc
Variant
Relatedalso


[PMID 21949331] 44 Tiling array shows low ANRIL, high CDKN2B expression associated with chromosome 9p21 coronary artery disease (CAD) risk genotype

[PMID 18987759OA-icon.png] Genetic testing for atherosclerosis risk: inevitability or pipe dream?

[PMID 19019192] Association of genetic variation on chromosome 9p21.3 and arterial stiffness.

[PMID 19214202OA-icon.png] Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis.

[PMID 19578366OA-icon.png] Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

[PMID 19888323OA-icon.png] Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.

[PMID 20403154OA-icon.png] Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population.