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rs2954029

From SNPedia

Orientationplus
Stabilizedplus
Make rs2954029(A;A)
Make rs2954029(A;T)
Make rs2954029(T;T)
ReferenceGRCh38 38.1/141
Chromosome8
Position125478730
is asnp
is mentioned by
dbSNPrs2954029
ebirs2954029
HLIrs2954029
Exacrs2954029
Varsomers2954029
Maprs2954029
PheGenIrs2954029
hapmaprs2954029
1000 genomesrs2954029
hgdprs2954029
ensemblrs2954029
gopubmedrs2954029
geneviewrs2954029
scholarrs2954029
googlers2954029
pharmgkbrs2954029
gwascentralrs2954029
openSNPrs2954029
23andMers2954029
23andMe allrs2954029
SNP Nexus

SNPshotrs2954029
SNPdbers2954029
MSV3drs2954029
GWAS Ctlgrs2954029
GMAF0.4412
Max Magnitude
? (A;A) (A;T) (T;T) 28
GWAS snp
PMID [PMID 24097068OA-icon.png]
Trait HDL cholesterol
Title Discovery and refinement of loci associated with lipid levels.
Risk Allele T
P-val 3E-29
Odds Ratio 0.04 [NR] unit increase
GWAS snp
PMID [PMID 24097068OA-icon.png]
Trait LDL cholesterol
Title Discovery and refinement of loci associated with lipid levels.
Risk Allele T
P-val 2E-50
Odds Ratio 0.056 [NR] unit decrease
GWAS snp
PMID [PMID 24097068OA-icon.png]
Trait Triglycerides
Title Discovery and refinement of loci associated with lipid levels.
Risk Allele T
P-val 1E-107
Odds Ratio 0.076 [NR] mg/dL decrease
GWAS snp
PMID [PMID 20864672OA-icon.png]
Trait Triglycerides
Title Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease
Risk Allele T
P-val 2E-11
Odds Ratio 0.04 [0.03-0.05] unit decrease
GWAS snp
PMID [PMID 20686565OA-icon.png]
Trait HDL cholesterol
Title Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele T
P-val 6E-19
Odds Ratio 0.61 [0.47-0.75] mg/dL increase
GWAS snp
PMID [PMID 20686565OA-icon.png]
Trait LDL cholesterol
Title Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele A
P-val 3E-29
Odds Ratio 1.84 [1.51-2.17] mg/dL decrease
GWAS snp
PMID [PMID 20686565OA-icon.png]
Trait Triglycerides
Title Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele T
P-val 3E-55
Odds Ratio 5.64 [4.88-6.4] mg/dL decrease
GWAS snp
PMID [PMID 20139978]
Trait Triglycerides
Title Genome-wide association study of hematological and biochemical traits in a Japanese population.
Risk Allele T
P-val 3E-7
Odds Ratio 0.076 [0.047-0.105] unit decrease
GWAS snp
PMID [PMID 19060906OA-icon.png]
Trait Triglycerides
Title Common variants at 30 loci contribute to polygenic dyslipidemia
Risk Allele T
P-val 3E-19
Odds Ratio 0.11 [0.07-0.15] SD decrease
GWAS snp
PMID [PMID 19060906OA-icon.png]
Trait Triglycerides
Title Common variants at 30 loci contribute to polygenic dyslipidemia.
Risk Allele T
P-val 3E-19
Odds Ratio 0.11 [0.07-0.15] s.d. decrease


[PMID 24922540OA-icon.png] Genetic Determinants of Long-Term Changes in Blood Lipid Concentrations: 10-Year Follow-Up of the GLACIER Study

[PMID 23832694] Common genetic variants associated with lipid profiles in a Chinese pediatric population.

[PMID 23202125OA-icon.png] Large-scale association analysis identifies new risk loci for coronary artery disease.

[PMID 21071687] TRIB1 and GCKR polymorphisms, lipid levels, and risk of ischemic heart disease in the general population.

[PMID 20160193OA-icon.png] Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.

[PMID 19656773OA-icon.png] A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

GET Evidence
rs2954029
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.335938
summary