Have questions? Visit https://www.reddit.com/r/SNPedia

rs2961920

From SNPedia

Orientationplus
Stabilizedplus
Make rs2961920(A;A)
Make rs2961920(A;C)
Make rs2961920(C;C)
ReferenceGRCh38 38.1/141
Chromosome5
Position160484499
GeneMIR146A
is asnp
is mentioned by
dbSNPrs2961920
ebirs2961920
HLIrs2961920
Exacrs2961920
Varsomers2961920
Maprs2961920
PheGenIrs2961920
hapmaprs2961920
1000 genomesrs2961920
hgdprs2961920
ensemblrs2961920
gopubmedrs2961920
geneviewrs2961920
scholarrs2961920
googlers2961920
pharmgkbrs2961920
gwascentralrs2961920
openSNPrs2961920
23andMers2961920
23andMe allrs2961920
SNP Nexus

SNPshotrs2961920
SNPdbers2961920
MSV3drs2961920
GWAS Ctlgrs2961920
GMAF0.3834
Max Magnitude
? (A;A) (A;C) (C;C) 28
[PMID 18474871OA-icon.png] This study compared 608 patients of European ancestry with papillary thyroid cancer, which is the most common form of thyroid cancer and is highly treatable, to 901 healthy controls. The authors found an association between the SNP rs2910164, which is equivalent to the 23andMe SNP rs2961920, and risk for thyroid cancer. People with the AC genotype at rs2961920 had about 1.5 times the odds of papillary thyroid cancer compared to those with the AA genotype and about three times the odds compared to the CC genotype. Though this is an atypical risk pattern, the researchers speculate in a separate paper that having one copy of each form of the SNP increases production of molecules that regulate the cell's response to DNA damage, a process that is often involved in cancer.