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rs2976392

From SNPedia

Orientationplus
Stabilizedplus
Make rs2976392(A;A)
Make rs2976392(A;G)
Make rs2976392(G;G)
ReferenceGRCh38 38.1/141
Chromosome8
Position142681514
GenePSCA
is asnp
is mentioned by
dbSNPrs2976392
ebirs2976392
HLIrs2976392
Exacrs2976392
Varsomers2976392
Maprs2976392
PheGenIrs2976392
hapmaprs2976392
1000 genomesrs2976392
hgdprs2976392
ensemblrs2976392
gopubmedrs2976392
geneviewrs2976392
scholarrs2976392
googlers2976392
pharmgkbrs2976392
gwascentralrs2976392
openSNPrs2976392
23andMers2976392
23andMe allrs2976392
SNP Nexus

SNPshotrs2976392
SNPdbers2976392
MSV3drs2976392
GWAS Ctlgrs2976392
GMAF0.4311
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 18488030] rs2976392 and diffuse-type gastric cancer (allele-specific odds ratio (OR) = 1.62, 95% CI = 1.38-1.89, P = 1.11 x 10(-9)). Substitution of the C allele with the risk allele T at a SNP in the first exon (rs2294008, which has r(2) = 0.995, D' = 0.999 with rs2976392) reduces transcriptional activity of an upstream fragment of the gene
OMIM137215
DescGASTRIC CANCER
Variant
Relatedalso
OMIM602470
DescPROSTATE STEM CELL ANTIGEN; PSCA
Variant
Relatedalso


[PMID 20131315] Genetic variation of PSCA gene is associated with the risk of both diffuse- and intestinal-gastric cancer in a Chinese population


[PMID 22481254] The PSCA polymorphisms derived from genome-wide association study are associated with risk of gastric cancer: a meta-analysis


[PMID 19554573] Two genetic variants in prostate stem cell antigen and gastric cancer susceptibility in a Chinese population.


[PMID 19582881] Association of prostate stem cell antigen gene polymorphisms with the risk of stomach cancer in Japanese.


[PMID 22037551] A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.


[PMID 22426141] Prostate stem cell antigen polymorphisms and susceptibility to gastric cancer: a systematic review and meta-analysis.


[PMID 25503145] PSCA and MUC1 Gene Polymorphisms Are Linked with Gastric Cancer and Pre-malignant Gastric Conditions


[PMID 26006239OA-icon.png] The Influence of PSCA Gene Variation on Its Expression and Gastric Adenocarcinoma Susceptibility in the Northwest Chinese Population


[PMID 26320491] Common Genetic Variants of PSCA, MUC1 and PLCE1 Genes are not Associated with Colorectal Cancer


[PMID 26848528] PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population.


[PMID 26891331] Impact of DCC (rs714) and PSCA (rs2294008 and rs2976392) Gene Polymorphism in Modulating Cancer Risk in Asian Population.