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rs3024493

From SNPedia

Orientationminus
Stabilizedminus
Make rs3024493(G;G)
Make rs3024493(G;T)
Make rs3024493(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position206770623
GeneIL10
is asnp
is mentioned by
dbSNPrs3024493
ebirs3024493
HLIrs3024493
Exacrs3024493
Varsomers3024493
Maprs3024493
PheGenIrs3024493
hapmaprs3024493
1000 genomesrs3024493
hgdprs3024493
ensemblrs3024493
gopubmedrs3024493
geneviewrs3024493
scholarrs3024493
googlers3024493
pharmgkbrs3024493
gwascentralrs3024493
openSNPrs3024493
23andMers3024493
23andMe allrs3024493
SNP Nexus

SNPshotrs3024493
SNPdbers3024493
MSV3drs3024493
GWAS Ctlgrs3024493
GMAF0.0854
Max Magnitude
? (G;G) (G;T) (T;T) 28
GWAS snp
PMID [PMID 19915572OA-icon.png]
Trait Ulcerative colitis
Title Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
Risk Allele
P-val 8E-8
Odds Ratio NR NR
GWAS snp
PMID [PMID 20228798]
Trait Ulcerative colitis
Title Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
Risk Allele T
P-val 1E-12
Odds Ratio 1.35 [1.22-1.50]


[PMID 16600026OA-icon.png] Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway.


[PMID 18635889OA-icon.png] Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.


[PMID 18640487OA-icon.png] Association of donor inflammation- and apoptosis-related genotypes and delayed allograft function after kidney transplantation.


[PMID 20509889OA-icon.png] The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study.


GET Evidence
rs3024493
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.109375
summary



[PMID 24130510OA-icon.png] Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression